Jesus taught we always live out what is in our heart. Our life is primarily directed by the deeply submerged core beliefs, which may often be very different from what we say we value or believe. One key component of inner formation is changing our core beliefs, with God's grace, and thus reducing the willing-doing gap. In the article, after identifying the problem, and highlighting Jesus’ focus on inner or heart formation, a basic overview of the concept of a belief (...) is presented. Then ten principles or features about core beliefs and formation are proposed and clarified, followed by some implications for practice. (shrink)

Evidence accumulates that pre- and postnatally circulating estrogens play an active role in the differentiation of the female brain: the susceptible period for feminization of the brain seems to extend far beyond the period during which masculinization of the brain occurs. Thus, there is a need to reevaluate the widely accepted “concept of basic femaleness” in sexual brain differentiation.

In this article we give a general categorical construction via reflection functors for various completions of T0-spaces subordinate to sobrification, with a particular emphasis on what we call the -completion, a type of directed completion introduced by Wyler [O. Wyler, Dedekind complete posets and Scott topologies, in: B. Banaschewski, R.-E. Hoffmann , Continuous Lattices Proceedings, Bremen 1979, in: Lecture Notes in Mathematics, vol. 871, Springer Verlag, 1981, pp. 384–389]. A key result is that all completions of a certain type are (...) universal, hence unique . We give a direct definition of the -completion and develop its theory by introducing a variant of the Scott topology, which we call the d-topology. For partially ordered sets the -completion turns out to be a natural dcpo-completion that generalizes the rounded ideal completion. In the latter part of the paper we consider settings in which the -completion agrees with the sobrification respectively the closed ideal completion. (shrink)

The meaning of optimality and economy in phylogenetics and evolutionary biology is discussed.It can be shown that the prevailing concepts of optimality and economy are equivocal as they are not based on strict theoretical positions and as they have a variable meaning in different theoretical contexts. The ideas of optimality and economy can be considered to be identical with the expectation of a relatively simple order in a particular field of study. Although there exists no way of inferring one or (...) several methods of solving scientific problems from the presupposed idea of economy and optimality, a lack of motivation for scientific investigations would result if the concepts of economy and optimality in nature were dropped. (shrink)

This thought-provoking book discusses the concept of progress in economics and investigates whether any advance has been made in its different spheres of research. The authors look back at the history, successes and failures of their respective fields and thoroughly examine the notion of progress from an epistemological and methodological perspective. The idea of progress is particularly significant as the authors regard it as an essentially contested concept which can be defined in many ways – theoretically or empirically; locally or (...) globally; or as encouraging or impeding the existence of other research traditions. The authors discuss the idea that for progress to make any sense there must be an accumulation of knowledge built up over time rather than the replacement of ideas by each successive generation. Accordingly, they are not concerned with estimating the price of progress, reminiscing in the past, or assessing what has been lost. Instead they apply the complex mechanisms and machinery of the discipline to sub-fields such as normative economics, monetary economics, trade and location theory, Austrian economics and classical economics to critically assess whether progress has been made in these areas of research. -/- Bringing together authoritative and wide-ranging contributions by leading scholars, this book will challenge and engage those interested in philosophy, economic methodology and the history of economic thought. It will also appeal to economists in general who are interested in the advancement of their profession. (shrink)

The National Science Foundation's Second Merit Criterion, or Broader Impacts Criterion , was introduced in 1997 as the result of an earlier Congressional movement to enhance the accountability and responsibility as well as the effectiveness of federally funded projects. We demonstrate that a robust understanding and appreciation of NSF BIC argues for a broader conception of research ethics in the sciences than is currently offered in Responsible Conduct of Research training. This essay advocates augmenting RCR education with training regarding broader (...) impacts. We demonstrate that enhancing research ethics training in this way provides a more comprehensive understanding of the ethics relevant to scientific research and prepares scientists to think not only in terms of responsibly conducted science, but also of the role of science in responding to identified social needs and in adhering to principles of social justice. As universities respond to the mandate from America COMPETES to “provide training and oversight in the responsible and ethical conduct of research”, we urge institutions to embrace a more adequate conception of research ethics, what we call the Ethical Dimensions of Scientific Research, that addresses the full range of ethical issues relevant to scientific inquiry, including ethical issues related to the broader impacts of scientific research and practice. (shrink)

This study builds upon the top management literature to predict and test antecedents to firms’ engagement in corruption. Building on a survey of 341 executives in India, we find that if executives have social ties with government officials, their firms are more likely to engage in corruption. Further, these executives are likely to rationalize engaging in corruption as a necessity for being competitive. The results collectively illustrate the role that executives’ social ties and perceptions have in shaping illegal actions of (...) their respective firms. (shrink)

Background: Although convolutional neural networks (CNNs) achieve high diagnostic accuracy for detecting Alzheimer’s disease (AD) dementia based on magnetic resonance imaging (MRI) scans, they are not yet applied in clinical routine. One important reason for this is a lack of model comprehensibility. Recently developed visualization methods for deriving CNN relevance maps may help to fill this gap as they allow the visualization of key input image features that drive the decision of the model. We investigated whether models with higher accuracy (...) also rely more on discriminative brain regions predefined by prior knowledge. Methods: We trained a CNN for the detection of AD in N = 663 T1-weighted MRI scans of patients with dementia and amnestic mild cognitive impairment (MCI) and verified the accuracy of the models via cross-validation and in three independent samples including in total N = 1655 cases. We evaluated the association of relevance scores and hippocampus volume to validate the clinical utility of this approach. To improve model comprehensibility, we implemented an interactive visualization of 3D CNN relevance maps, thereby allowing intuitive model inspection. Results: Across the three independent datasets, group separation showed high accuracy for AD dementia versus controls (AUC ≥ 0.91) and moderate accuracy for amnestic MCI versus controls (AUC ≈ 0.74). Relevance maps indicated that hippocampal atrophy was considered the most informative factor for AD detection, with additional contributions from atrophy in other cortical and subcortical regions. Relevance scores within the hippocampus were highly correlated with hippocampal volumes (Pearson’s r ≈ −0.86, p < 0.001). Conclusion: The relevance maps highlighted atrophy in regions that we had hypothesized a priori. This strengthens the comprehensibility of the CNN models, which were trained in a purely data-driven manner based on the scans and diagnosis labels. The high hippocampus relevance scores as well as the high performance achieved in independent samples support the validity of the CNN models in the detection of AD-related MRI abnormalities. The presented data-driven and hypothesis-free CNN modeling approach might provide a useful tool to automatically derive discriminative features for complex diagnostic tasks where clear clinical criteria are still missing, for instance for the differential diagnosis between various types of dementia. (shrink)

In der 1970 gegründeten Reihe erscheinen Arbeiten, die philosophiehistorische Studien mit einem systematischen Ansatz oder systematische Studien mit philosophiehistorischen Rekonstruktionen verbinden. Neben deutschsprachigen werden auch englischsprachige Monographien veröffentlicht. Gründungsherausgeber sind: Erhard Scheibe (Herausgeber bis 1991), Günther Patzig (bis 1999) und Wolfgang Wieland (bis 2003). Von 1990 bis 2007 wurde die Reihe von Jürgen Mittelstraß mitherausgegeben.

Aristoteles’ Traktat De anima untersucht die Natur der Seele. Unter ›Seele‹ ist dabei jedoch nicht das subjektive Zentrum unseres mentalen Lebens zu verstehen, sondern dasjenige Prinzip, dessen Vorhandensein lebendige von leblosen Körpern unterscheidet. Es umfasst alle Formen des Lebendigen, also pflanzliches, tierisches und menschliches Leben. Ziel der Schrift ist es, die Seele zu definieren, d.h. zu erklären, was es für diese Formen des Lebendigen jeweils heißt, lebendig zu sein. Diskutiert werden: der vegetative Selbsterhalt, Wahrnehmung, menschliches Denken sowie die Ortsbewegung der (...) Lebewesen. De anima gehört zu den faszinierendsten, philosophisch lohnendsten, aber auch schwierigeren Schriften des Aristoteles. Die zweisprachige Studienausgabe bietet eine vollständige Neu­übersetzung. Benutzt wird die Edition des griechischen Textes von Aurelius Förster (Budapest 1912), von der sich die heutzutage sehr verbreitete Ausgabe von W. D. Ross textkritisch hat leiten lassen (OCT 1956 und 1971). Sie ist auch durch die späteren Ausgaben von Siwek (Rom 1965) und Jannone (Paris 1966) nicht ersetzt. Eine Einleitung führt in die Grundlagen und Voraussetzungen der aristotelischen Seelenlehre ein und gibt einen Überblick über den Gedankengang der Schrift. Der Kommentarteil ist so knapp wie möglich gehalten. Im Anhang sind ein Glossar und ein Verzeichnis der Abweichungen von der Ausgabe von Ross beigefügt. (shrink)

Recent efforts in a range of scientific fields have emphasised research and methods concerning individual differences and individualisation. This article brings together various scientific disciplines—ecology, evolution, and animal behaviour; medicine and psychiatry; public health and sport/exercise science; sociology; psychology; economics and management science—and presents their research on individualisation. We then clarify the concept of individualisation as it appears in the disciplinary casework by distinguishing three kinds of individualisation studied in and across these disciplines: Individualisation ONE as creating/changing individual differences (the (...) process that generates differences between individuals: intrapopulation or intraspecific variation/heterogeneity); Individualisation TWO as individualising applications (the tailoring or customising of something—information, treatment, a product or service, etc.—for an individual or specific group of individuals); and Individualisation THREE as social changes influencing autonomy, risk, and responsibilities (the process discussed under the rubric of sociological individualisation theory). Moreover, we analyse conceptual links between individualisation and individuality, and characterise different sorts of individuality that the disciplines study. This paper aims to promote interdisciplinary research concerning individualisation by establishing a common conceptual-theoretical basis, while leaving room for disciplinary differences. (shrink)

In this essay we develop and argue for the adoption of a more comprehensive model of research ethics than is included within current conceptions of responsible conduct of research (RCR). We argue that our model, which we label the ethical dimensions of scientific research (EDSR), is a more comprehensive approach to encouraging ethically responsible scientific research compared to the currently typically adopted approach in RCR training. This essay focuses on developing a pedagogical approach that enables scientists to better understand and (...) appreciate one important component of this model, what we call intrinsic ethics . Intrinsic ethical issues arise when values and ethical assumptions are embedded within scientific findings and analytical methods. Through a close examination of a case study and its application in teaching, namely, evaluation of climate change integrated assessment models, this paper develops a method and case for including intrinsic ethics within research ethics training to provide scientists with a comprehensive understanding and appreciation of the critical role of values and ethical choices in the production of research outcomes. (shrink)

Klaus Schwarzfischer zeigt, wie wichtig es ist, mit dem einfachsten Fall einer ästhetischen Erfahrung zu beginnen. Die individuell-kognitiven Perspektiven und die sozial-kommunikativen Prozesse werden in einer einheitlichen Theorie analysierbar. Die Evolution wird dabei ebenso berücksichtigt wie neurobiologische Aspekte. Interdisziplinär verständlich und ausführlich illustriert werden die Basis-Konzepte dargestellt. Schritt für Schritt nachvollziehbar werden auch komplexere Anwendungen entwickelt: Von der Gestalt zur Gestaltung. Was genau ist eine ästhetische Erfahrung? Welcher biologische Mechanismus liegt jeder ästhetischen Erfahrung zugrunde? Warum haben sich ästhetische Erfahrungen (...) aus evolutionärer Perspektive durchgesetzt? Haben nur Menschen ästhetische Erfahrungen? Was ist der Gültigkeitsbereich ästhetischer Beobachtungen? (Was alles kann eine ästhetische Erfahrung auslösen?) Warum sind Destruktion und Provokation sowie Ironie und Humor auch ästhetische Phänomene? Wie können die „Gestalt-Gesetze“ als Symmetrien (d.h. als Invarianzen) interpretiert werden, um so mit Semiotik und Systemtheorie kompatibel zu werden? (shrink)

*******Résume en français plus bas****** Karl Kraus’s favourable and conceptually complex comments of the portrait drawings byOskar Kokoschka in 1910 put us on the trail of a host of different phenomena of pictorial representation. Based on close-readings of several aphorisms by Kraus and drawings by Kokoschka, I suggest that there is something like realistic distortion and that the traditional concepts of style cannot account for all essential stylistic variations that are important in pictures. I argue that we need to introduce (...) the concept of subject specific style. This must be distinguished from other concepts such as signature style. I try to show how these conceptual distinctions are connected to the difference in representational range displayed by media that are based on traces, like photography, and by media based on testimony, like drawing or writing. *********** Résumé En 1910, Oskar Kokoschka produit une série de dessins pour la revue expressionniste berlinoise Der Sturm. L’un des portraits représente le satiriste Karl Kraus, un autre l’architecte Adolf Loos. Au même moment, Kraus fait paraître une série d’aphorismes qui commentent le travail de Kokoschka. Kraus part du travail de Kokoschka pour arriver à des principes généraux sur la représentation picturale. Une analyse des réflexions de l’écrivain et des deux dessins faits par Kokoschka nous permet non seulement de mieux comprendre comment un dessin peut saisir le caractère d’un modèle au-delà du physique, mais aussi de forger des concepts pour enrichir les notions de style traditionnelles. Nous soutenons dans notre article qu’il faut introduire l’idée d’un style à l’oeuvre pour compléter les notions de style habituelles.Le style à l’oeuvre peut être spécifique au sujet traité. Nous montrons en particulier comment le dessin permet des distorsions réalistes, difficiles à obtenir dans des médias basés sur la trace comme la photographie. (shrink)

Most people encounter art images as digital reproductions on a computer screen instead of as originals in a museum or gallery. With the development of digital technologies, high-resolution artworks can be accessed anywhere and anytime by a large number of viewers. Since these digital images depict the same content and are attributed to the same artist as the original, it is often implicitly assumed that their aesthetic evaluation will be similar. When it comes to the digital reproductions of art, however, (...) it is also obvious that reproductions do differ from the originals in various aspects. Besides image quality, resolution, and format, the most obvious change is in the representation of color. The effects of subjectively varying surface-level image features on art evaluation have not been clearly assessed. To address this gap, we compare the evaluation of digital reproductions of 16 expressionist and impressionist paintings manipulated to have a high color saturation vs. a saturation similar to the original. We also investigate the impact of viewing time and expertise, two other aspects that may impact the perception of art in online contexts. Moreover, we link these dimensions to a recent model of aesthetic experience [the Vienna Integrated Model of Top-Down and Bottom-Up Processes in Art Perception ]. Results suggest that color saturation does not exert a major influence on liking. Cognitive and emotional aspects, however, are affected – to different extents for experts and laypersons. For laypersons, the increase in color saturation led to more positive assessments of an artwork, whereas it resulted in increased confusion for art experts. This insight is particularly important when it comes to reproducing artworks digitally. Depending on the intended use, increasing or decreasing the color saturation of the digitally reproduced image might be most appropriate. We conclude with a discussion of these findings and address the question of why empirical aesthetics requires more precise dimensions to better understand the subtle processes that take place in the perception of today’s digitally reproduced art environment. (shrink)